Simultaneous Transmission and Reception: Algorithm, Design and System Level Performance

Full Duplex or Simultaneous transmission and reception (STR) in the same frequency at the same time can potentially double the physical layer capacity. However, high power transmit signal will appear at receive chain as echoes with powers much higher than the desired received signal. Therefore, in order to achieve the potential gain, it is imperative to cancel these echoes. As these high power echoes can saturate low noise amplifier (LNA) and also digital domain echo cancellation requires unrealistically high resolution analog-to-digital converter (ADC), the echoes should be cancelled or suppressed sufficiently before LNA. In this paper we present a closed-loop echo cancellation technique which can be implemented purely in analogue domain. The advantages of our method are multiple-fold: it is robust to phase noise, does not require additional set of antennas, can be applied to wideband signals and the performance is irrelevant to radio frequency (RF) impairments in transmit chain. Next, we study a few protocols for STR systems in carrier sense multiple access (CSMA) network and investigate MAC level throughput with realistic assumptions in both single cell and multiple cells. We show that STR can reduce hidden node problem in CSMA network and produce gains of up to 279% in maximum throughput in such networks. Finally, we investigate the application of STR in cellular systems and study two new unique interferences introduced to the system due to STR, namely BS-BS interference and UE-UE interference. We show that these two new interferences will hugely degrade system performance if not treated appropriately. We propose novel methods to reduce both interferences and investigate the performances in system level.Comment: 20 pages. This manuscript will appear in the IEEE Transactions on Wireless Communication

Wideband Self-Adaptive RF Cancellation Circuit for Full-Duplex Radio: Operating Principle and Measurements

This paper presents a novel RF circuit architecture for self-interference cancellation in inband full-duplex radio transceivers. The developed canceller is able to provide wideband cancellation with waveform bandwidths in the order of 100 MHz or beyond and contains also self-adaptive or self-healing features enabling automatic tracking of time-varying self-interference channel characteristics. In addition to architecture and operating principle descriptions, we also provide actual RF measurements at 2.4 GHz ISM band demonstrating the achievable cancellation levels with different bandwidths and when operating in different antenna configurations and under low-cost highly nonlinear power amplifier. In a very challenging example with a 100 MHz waveform bandwidth, around 41 dB total cancellation is obtained while the corresponding cancellation figure is close to 60 dB with the more conventional 20 MHz carrier bandwidth. Also, efficient tracking in time-varying reflection scenarios is demonstrated.Comment: 7 pages, to be presented in 2015 IEEE 81st Vehicular Technology Conferenc

Inhibition of poly(ADP-ribose)polymerase binding to DNA by thymidine dimer

AbstractThe ability of poly(ADP-ribose)polymerase to bind damaged DNA was assessed by electrophoretic mobility shift assay. DNA binding domain of poly(ADP-ribose)polymerase (PARPDBD) binds to synthetic deoxyribonucleotide duplex 10-mer. However, the synthetic deoxyribonucleotide duplex containing cys-syn thymidine dimer which produces the unwinding of DNA helix structure lost its affinity to PARPDBD. It was shown that the binding of PARPDBD to the synthetic deoxyribonucleotide duplex was not affected by O6-Me-dG which causes only minor distortion of DNA helix structure. This study suggests that the stabilized DNA helix structure is important for poly(ADP-ribose)polymerase binding to DNA breaks, which are known to stimulate catalytic activity of poly(ADP-ribose)polymerase

Luminance enhancement of electroluminescent devices using highly dielectric UV-curable polymer and oxide nanoparticle composite

A flexible hybrid structure electroluminescent (HSEL) device was fabricated from ZnS:Cu phosphor microparticles dispersed in a UVcurable polymer matrix. We observed a maximum luminance of 111 cd/m2 at 10 kHz and 170 V from a device wherein the mixing ratio between the phosphor particles and highly dielectric polymer binder was 70:30 wt%. Furthermore, by uniformly dispersing highly dielectric BaTiO3 nanoparticles within the polymer matrix, we were able to obtain a luminance of up to 211 cd/m2 in the HSEL device. Compared to the conventional thermal curing process, this UV process greatly simplifies the fabrication steps by combining phosphors and dielectric materials at room temperature. This process also demonstrates a promising pathway toward creating flexible and printed EL devices in the future. © 2014 Optical Society of America.1

Fluoxetine Up-Regulates Bcl-xL Expression in Rat C6 Glioma Cells

Objective To analyze both differentially expressed genes and the Bcl-xL protein expression after acute and chronic treatment with fluoxetine in rat C6 glioma cells. Methods C6 glioma cells were cultured for 24 h or 72 h after treatment with 10 mu M fluoxetine, and gene expression patterns were observed using microarray and qRT-PCR. Then, cells were cultured for 6 h, 24 h, 72 h or 96 h after treatment with 10 mu M fluoxetine, and the expression of Bd-xL protein was measured using western blot. Results As determined by microarray, treatment with fluoxetine for 24 h up-regulated 33 genes (including Bcl-xL and NCAM140) and down-regulated 7 genes (including cyclin G-associated kinase). Treatment with fluoxetine for 72 h up-regulated 53 genes (including Gs alpha and Bcl-xL) and down-regulated 77 genes (including Gai2 and annexin V). Based on the qRT-PCR results, there was an increase in Gsa mRNA and a decrease in G alpha i2 mRNA at 72 h in fluoxetine-treated cells as compared to control, a result that was consistent with microarray. We also observed an increase in Bcl-xL mRNA (both at 24 h and at 72 h) in fluoxetine-treated cells as compared to control, demonstrating a tendency to increase gradually. Bcl-xL protein expression increased as the duration of fluoxetine treatment increased. Conclusion These results suggest that chronic treatment with fluoxetine not only initiates the cAMP pathway through inducing Gsa expression but also induces Bcl-xL expression, thus inhibiting apoptosis. Psychiatry Investig 2011;8:161-168This work was supported by the research fund of Hanyang University (HY-2010-N)